LOCUS       NM_007553               1541 bp    mRNA    linear   ROD 07-JAN-2002
DEFINITION  Mus musculus bone morphogenetic protein 2 (Bmp2), mRNA.
ACCESSION   NM_007553
VERSION     NM_007553.1  GI:6680793
KEYWORDS    .
SOURCE      house mouse.
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Rodentia; Sciurognathi; Muridae; Murinae; Mus.
REFERENCE   1  (bases 1 to 1541)
  AUTHORS   Feng,J.Q., Harris,M.A., Ghosh-Choudhury,N., Feng,M., Mundy,G.R. and
            Harris,S.E.
  TITLE     Structure and sequence of mouse bone morphogenetic protein-2 gene
            (BMP-2): comparison of the structures and promoter regions of BMP-2
            and BMP-4 genes
  JOURNAL   Biochim. Biophys. Acta 1218 (2), 221-224 (1994)
  MEDLINE   94289485
REFERENCE   2  (bases 1 to 1541)
  AUTHORS   Heller,L.C., Li,Y., Abrams,K.L. and Rogers,M.B.
  TITLE     Transcriptional regulation of the Bmp2 gene. Retinoic acid
            induction in F9 embryonal carcinoma cells and Saccharomyces
            cerevisiae
  JOURNAL   J. Biol. Chem. 274 (3), 1394-1400 (1999)
  MEDLINE   99098878
   PUBMED   9880512
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from L25602.1.
FEATURES             Location/Qualifiers
     source          1..1541
                     /organism="Mus musculus"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 76.1 cM"
                     /cell_type="spleen"
     gene            1..1541
                     /gene="Bmp2"
                     /db_xref="LocusID:12156"
                     /db_xref="MGD:88177"
     CDS             357..1541
                     /gene="Bmp2"
                     /codon_start=1
                     /db_xref="LocusID:12156"
                     /db_xref="MGD:88177"
                     /product="bone morphogenetic protein 2"
                     /protein_id="NP_031579.1"
                     /db_xref="GI:6680794"
                     /translation="MVAGTRCLLVLLLPQVLLGGAAGLIPELGRKKFAAASSRPLSRP
                     SEDVLSEFELRLLSMFGLKQRPTPSKDVVVPPYMLDLYRRHSGQPGAPAPDHRLERAA
                     SRANTVRTFHQLEAVEELPEMSGKTARRFFFNLSSVPSDEFLTSAELQIFREQIQEAL
                     GNSSFQHRINIYEIIKPAAANLKFPVTRLLDTRLVNQNTSQWESFDVTPAVMRWTTQG
                     HTNHGFVVEVAHLEENPGVSKRHVRISRSLHQDEHSWSQIRPLLVTFGHDGKGHPLHK
                     REKRQAKHKQRKRLKSSCKRHPLYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADH
                     LNSTNHAIVQTLVNSVNSKIPKACCVPTELSAISMLYLDENEKVVLKNYQDMVVEGCG
                     CR"
     misc_feature    492..1154
                     /note="TGFb_propeptide; Region: TGF-beta propeptide"
     misc_feature    1236..1538
                     /note="TGFB; Region: Transforming growth  factor-beta
                     (TGF-beta) family"
     misc_feature    1236..1538
                     /note="TGF-beta; Region: Transforming growth factor beta
                     like domain"
BASE COUNT      361 a    444 c    414 g    322 t
ORIGIN      
        1 cgcactcctc cccctgctcg aggctgtgtg tcagcacttg gctggagact tcttgaactt
       61 gccgggagag tgacttgggc tccccacttc gcgccggtgt cctcgcccgg cggatccagt
      121 cttgccgcct ccagcccgat cacctctctt cctcagcccg ctggcccacc ccaagacaca
      181 gttccctaca gggagaacac ccggagaagg aggaggaggc gaagaaaagc aacagaagcc
      241 cagttgctgc tccaggtccc tcggacagag ctttttccat gtggagactc tctcaatgga
      301 cgtgccccct agtgcttctt agacggactg cggtctccta aagccgcagg tcgaccatgg
      361 tggccgggac ccgctgtctt ctagtgttgc tgcttcccca ggtcctcctg ggcggcgcgg
      421 ccggcctcat tccagagctg ggccgcaaga agttcgccgc ggcatccagc cgacccttgt
      481 cccggccttc ggaagacgtc ctcagcgaat ttgagttgag gctgctcagc atgtttggcc
      541 tgaagcagag acccaccccc agcaaggacg tcgtggtgcc cccctatatg ctagatctgt
      601 accgcaggca ctcaggccag ccaggagcgc ccgccccaga ccaccggctg gagagggcag
      661 ccagccgcgc caacaccgtg cgcacgttcc atcaactaga agccgtggag gaacttccag
      721 agatgagtgg gaaaacggcc cggcgcttct tcttcaattt aagttctgtc cccagtgacg
      781 agtttctcac atctgcagaa ctccagatct tccgggaaca gatacaggaa gctttgggaa
      841 acagtagttt ccagcaccga attaatattt atgaaattat aaagcctgca gcagccaact
      901 tgaaatttcc tgtgaccaga ctattggaca ccaggttagt gaatcagaac acaagtcagt
      961 gggagagctt cgacgtcacc ccagctgtga tgcggtggac cacacaggga cacaccaacc
     1021 atgggtttgt ggtggaagtg gcccatttag aggagaaccc aggtgtctcc aagagacatg
     1081 tgaggattag caggtctttg caccaagatg aacacagctg gtcacagata aggccattgc
     1141 tagtgacttt tggacatgat ggaaaaggac atccgctcca caaacgagaa aagcgtcaag
     1201 ccaaacacaa acagcggaag cgcctcaagt ccagctgcaa gagacaccct ttgtatgtgg
     1261 acttcagtga tgtggggtgg aatgactgga tcgtggcacc tccgggctat catgcctttt
     1321 actgccatgg ggagtgtcct tttccccttg ctgaccacct gaactccact aaccatgcca
     1381 tagtgcagac tctggtgaac tctgtgaatt ccaaaatccc taaggcatgc tgtgtcccca
     1441 cagagctcag cgcaatctcc atgttgtacc tagatgaaaa tgaaaaggtt gtgctaaaaa
     1501 attatcagga catggttgtg gagggctgcg ggtgtcgtta g
//